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General information
Gene symbol MSH6
Gene name mutS homolog 6
Chromosome 2
Chromosomal band p16
Imprinted Unknown
Genomic reference LRG_219
Transcript reference NM_000179.2
Associated with diseases ?, AML, CRC, Lynch Syndrome, MINAS, MRTES, polyposis, adenoma, cancer, cancer, bladder, cancer, brain, cancer, breast, cancer, endometrial, cancer, gastric (Neoplasm of stomach), cancer, ovarian, cancer, pancreatic, cancer, prostate, cancer, rectal, cancer, skin, squamous cell carcinoma, Esophageal cancer, glioma, malignant
Citation reference(s) -
Curators (3) John Paul Plazzer, Johan den Dunnen and Bryony A Thompson
Total number of public variants reported 2088
Unique public DNA variants reported 683
Individuals with public variants 1771
Hidden variants 1
Date created December 02, 2015
Date last updated November 24, 2017
Version MSH6:171124

Graphical displays and utilities
Graphs Graphs displaying summary information of all variants in the database »
UCSC Genome Browser Show variants in the UCSC Genome Browser (full view, compact view)
Ensembl Genome Browser Show variants in the Ensembl Genome Browser (full view, compact view)
NCBI Sequence Viewer Show distribution histogram of variants in the NCBI Sequence Viewer

Links to other resources
HGNC 7329
Entrez Gene 2956
PubMed articles MSH6
OMIM - Gene 600678
OMIM - Diseases AML (leukemia, myeloid, acute (AML))
CRC (cancer, colorectal (CRC))
Lynch Syndrome (cancer, colorectal, nonpolyposis, hereditary, type 1 (Lynch syndrome, HNPCC-1))
MRTES (Muir-Torre Syndrome)
cancer, bladder
cancer, endometrial
cancer, gastric (Neoplasm of stomach)
cancer, ovarian
cancer, pancreatic
cancer, prostate
Esophageal cancer


Active transcripts


ID     

Chr     

Name     

NCBI ID     

NCBI Protein ID     

DescendingVariants     
00000003 2 mutS homolog 6 (E. coli), transcript variant 1 NM_000179.2 NP_000170.1 2088


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