MLH3 gene homepage

General information
Gene symbol MLH3
Gene name mutL homolog 3
Chromosome 14
Chromosomal band q24.3
Imprinted Unknown
Genomic reference LRG_217
Transcript reference NM_001040108.1
Associated with diseases ?, AML, cancer, gastric, CRC, Lynch Syndrome, MINAS, MRTES, polyposis, polyps, adenoma, cancer, cancer, bladder, cancer, brain, cancer, breast, cancer, endometrial, cancer, ovarian, cancer, pancreatic, cancer, rectal, cancer, skin, squamous cell carcinoma, Esophageal cancer, glioma, malignant, in silico,
Citation reference(s) -
Curators (1) John Paul Plazzer
Total number of public variants reported 0
Unique public DNA variants reported 0
Individuals with public variants 0
Hidden variants 0
Date created January 27, 2016
Date last updated November 04, 2018
Version MLH3:181104

Links to other resources
HGNC 7128
Entrez Gene 27030
PubMed articles MLH3
OMIM - Gene 604395
OMIM - Diseases AML (leukemia, myeloid, acute (AML))
cancer, gastric (cancer, gastric (neoplasm of stomach))
CRC (cancer, colorectal (CRC))
Lynch Syndrome (cancer, colorectal, nonpolyposis, hereditary, type 1 (Lynch syndrome, HNPCC-1))
MRTES (Muir-Torre Syndrome)
cancer, bladder
cancer, endometrial
cancer, ovarian
cancer, pancreatic
Esophageal cancer

Active transcripts




NCBI ID     

NCBI Protein ID     

00000008 14 mutL homolog 3 (E. coli), transcript variant 1 NM_001040108.1 NP_001035197.1 0

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