Disease #00014

Official abbreviation -
Name cancer, brain
OMIM ID -
Individuals reported having this disease 16
Phenotype entries for this disease 17
Associated with 4 genes FBXO11, MLH3, MSH3, MUTYH
Associated tissues brain
Disease features -
Remarks -


Individuals

16 entries on 1 page. Showing entries 1 - 16.
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00002902 - - FI - Family fulfills Amsterdam or Bethesda criteria.; InSiGHT LOVDv2 ID:1008357; This data has been transferred from InSiGHT LOVDv2 database. - A+;B+; - cancer, brain Additional info: colon ca (61), breast ca (69) MSH6 MSH6 1 1 Michael Woods
00003220 - ? - - InSiGHT LOVDv2 ID:37; This data has been transferred from InSiGHT LOVDv2 database. - - - cancer, brain Additional info: childhood-onset brain tumor, lymphoma, colorectal cancer and neurofibromatosis type 1; MSH6 MSH6 2 1 Michael Woods
00016242 - ? - - InSiGHT LOVDv2 ID:63; - - - cancer, brain, cancer, kidney, other >6 café-au-lait spots, glioblastoma, young onset(4), Wilm's tumor MLH1 MLH1 2 1 Michael Woods
00016294 Wagner et al, 2003, Poley et al. 2007 M NL - from large family (20028); boy 4y, >6 café-au lait spots;InSiGHT LOVDv2 ID:193; - - - cancer, brain, cancer, kidney, other café-au lait spots, glioblastoma, tumor, Wilms MLH1 MLH1 1 1 Carli Tops
00017306 Wagner et al, 2003, Poley et al. 2007 M NL - from large family (20028); boy 4y, >6 café-au lait spots;InSiGHT LOVDv2 ID:1003271; - - - cancer, brain, cancer, kidney, other café-au lait spots, glioblastoma, tumor, Wilms MLH1 MLH1 1 1 Carli Tops
00018644 - ? - - InSiGHT LOVDv2 ID:1004646; - - - cancer, brain, cancer, kidney glioblastoma, Wilm's tumor MLH1 MLH1 1 1 Michael Woods
00020364 - ? - - InSiGHT LOVDv2 ID:1006529; - - - CRC, cancer, brain colon cancer (46), glioblastoma multiforme grade IV brain tumor (22) MLH1 MLH1 1 1 Michael Woods
00020365 - ? - - InSiGHT LOVDv2 ID:1006530; - - - CRC, cancer, brain colon cancer (50), colon cancer (53), hemangiomablastoma brain tumor (44) MLH1 MLH1 1 1 Michael Woods
00023058 - ? - - InSiGHT LOVDv2 ID:11; - - - cancer, brain brain tumor, lymphoma, young onset MSH2 MSH2 2 1 Michael Woods
00023521 Marafie et al., 2009 M Kuwait Arab InSiGHT LOVDv2 ID:1011249; Yes AII+ - cancer, brain Brain (20y) MSH2 MSH2 1 1 Makia Marafie
00023930 - ? - - InSiGHT LOVDv2 ID:1000120; - - - cancer, brain brain tumor, lymphoma, young onset MSH2 MSH2 1 1 Michael Woods
00025807 - M UK - also found to have MUTYH c.1331A>G;InSiGHT LOVDv2 ID:1017193; Yes AI- - cancer, brain astrocytoma aged 28 and crc at 34 MSH2 MSH2 1 1 Demetra Georgiou
00026365 - ? - - InSiGHT LOVDv2 ID:1000121; - - - cancer, brain brain tumors (multiple family members) MSH2 MSH2 1 1 Michael Woods
00027847 - F (UK) Caucasian Patient and sister deceased with PNET, suspected CMMRD. Tumours in both found to be negative for PMS2 staining (normal & tumour cells). Compound heterozygosity for c.1A>G and c.137G>T confirmed by parental testing. No known phenotype in parents.;InSiGHT LOVDv2 ID:1017231; Yes - - cancer, brain Loss of PMS2 in paediatric PNET PMS2 PMS2 2 1 Ian Berry
00027893 - M NL - InSiGHT LOVDv2 ID:1011018; - - - cancer, brain - PMS2 PMS2 2 1 Carli Tops
00028120 - M - - InSiGHT LOVDv2 ID:1017274; Yes - - cancer, brain brain (5y) PMS2 PMS2 2 1 Julia Vogt
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